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Gingerol suppresses sepsis-induced acute kidney injury by modulating methylsulfonylmethane and dimethylamine production

Acute kidney injury (AKI) and metabolic dysfunction are critical complications in sepsis syndrome; however, their pathophysiological mechanisms remain poorly understood. Therefore, we evaluated whether the pharmacological properties of 6-gingerol (6G) and 10-gingerol (10G) could modulate AKI and met...

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Detalles Bibliográficos
Autores principales: Rodrigues, Francisco Adelvane de Paulo, Santos, Alan Diego da Conceição, de Medeiros, Pedro Henrique Quintela Soares, Prata, Mara de Moura Gondim, Santos, Tailane Caína de Souza, da Silva, James Almada, Brito, Gerly Anne de Castro, dos Santos, Armênio Aguiar, Silveira, Edilberto Rocha, Lima, Aldo Ângelo Moreira, Havt, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092401/
https://www.ncbi.nlm.nih.gov/pubmed/30108263
http://dx.doi.org/10.1038/s41598-018-30522-6