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SOX2 recruits KLF4 to regulate nasopharyngeal carcinoma proliferation via PI3K/AKT signaling

SOX2 is a transcription factor that contributes to transcription modification and cancer, but the mechanism by which SOX2 regulates nasopharyngeal carcinoma cell proliferation is not well understood. Here, we identify a SOX2 signaling pathway that facilitates nasopharyngeal carcinoma, where it is up...

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Detalles Bibliográficos
Autores principales: Tang, Jianming, Zhong, Guansheng, Wu, Jianhui, Chen, Haiyan, Jia, Yongshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092437/
https://www.ncbi.nlm.nih.gov/pubmed/30108202
http://dx.doi.org/10.1038/s41389-018-0074-2