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Detection of KIT mutations in core binding factor acute myeloid leukemia

We have investigated the frequency and the effect of KIT mutations on the outcome of patients with CBF-AML. 69 patients (34 pediatrics and 35 adults) with CBF-AML were enrolled in the study. The frequency of KIT mutations was higher in adults compared to pediatrics (22.9% and 14.7%, p = 0.38) respec...

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Detalles Bibliográficos
Autores principales: Badr, Passant, Elsayed, Ghada M, Eldin, Dalia Negm, Riad, Bahia Y, Hamdy, Nayera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092444/
https://www.ncbi.nlm.nih.gov/pubmed/30112273
http://dx.doi.org/10.1016/j.lrr.2018.06.004