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The role of FLT3 inhibitors as maintenance therapy following hematopoietic stem cell transplant
Activating mutations in FLT3 in acute myeloid leukemia (AML) portend a poor prognosis, and targeting FLT3 with a tyrosine kinase inhibitor has been an area of intense research recently. Most FLT3 mutated AML patients undergo hematopoietic stem cell transplantation (HSCT) as standard of care but a si...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092446/ https://www.ncbi.nlm.nih.gov/pubmed/30112274 http://dx.doi.org/10.1016/j.lrr.2018.06.003 |