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Targeting Cyclin-Dependent Kinases for Treatment of Gynecologic Cancers

Ovarian, uterine/endometrial, and cervical cancers are major gynecologic malignancies estimated to cause nearly 30,000 deaths in 2018 in US. Defective cell cycle regulation is the hallmark of cancers underpinning the development and progression of the disease. Normal cell cycle is driven by the coor...

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Detalles Bibliográficos
Autores principales: Lin, Z. Ping, Zhu, Yong-Lian, Ratner, Elena S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092490/
https://www.ncbi.nlm.nih.gov/pubmed/30135856
http://dx.doi.org/10.3389/fonc.2018.00303