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The Parkinson's disease gene product DJ-1 modulates miR-221 to promote neuronal survival against oxidative stress
DJ-1 is a highly conserved protein that protects neurons against oxidative stress and whose loss of function mutations are linked to recessively inherited Parkinson's disease (PD). While a number of signaling pathways have been shown to be regulated by DJ-1, its role in controlling cell surviva...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092527/ https://www.ncbi.nlm.nih.gov/pubmed/30107296 http://dx.doi.org/10.1016/j.redox.2018.07.021 |