The Parkinson's disease gene product DJ-1 modulates miR-221 to promote neuronal survival against oxidative stress

DJ-1 is a highly conserved protein that protects neurons against oxidative stress and whose loss of function mutations are linked to recessively inherited Parkinson's disease (PD). While a number of signaling pathways have been shown to be regulated by DJ-1, its role in controlling cell surviva...

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Detalles Bibliográficos
Autores principales: Oh, Stephanie E., Park, Hye-Jin, He, Liqiang, Skibiel, Catherine, Junn, Eunsung, Mouradian, M. Maral
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092527/
https://www.ncbi.nlm.nih.gov/pubmed/30107296
http://dx.doi.org/10.1016/j.redox.2018.07.021

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