Cargando…

Total flavone of Abelmoschus manihot suppresses epithelial-mesenchymal transition via interfering transforming growth factor-β1 signaling in Crohn’s disease intestinal fibrosis

AIM: To explore the role and mechanism of total flavone of Abelmoschus manihot (TFA) on epithelial-mesenchymal transition (EMT) progress of Crohn’s disease (CD) intestinal fibrosis. METHODS: First, CCK-8 assay was performed to assess TFA on the viability of intestinal epithelial (IEC-6) cells and se...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Bo-Lin, Zhu, Ping, Li, You-Ran, Xu, Min-Min, Wang, Hao, Qiao, Li-Chao, Xu, Hai-Xia, Chen, Hong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092575/
https://www.ncbi.nlm.nih.gov/pubmed/30122880
http://dx.doi.org/10.3748/wjg.v24.i30.3414