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A high‐throughput method to identify trans‐activation domains within transcription factor sequences

Even though transcription factors (TFs) are central players of gene regulation and have been extensively studied, their regulatory trans‐activation domains (tADs) often remain unknown and a systematic functional characterization of tADs is lacking. Here, we present a novel high‐throughput approach t...

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Detalles Bibliográficos
Autores principales: Arnold, Cosmas D, Nemčko, Filip, Woodfin, Ashley R, Wienerroither, Sebastian, Vlasova, Anna, Schleiffer, Alexander, Pagani, Michaela, Rath, Martina, Stark, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092621/
https://www.ncbi.nlm.nih.gov/pubmed/30006452
http://dx.doi.org/10.15252/embj.201798896