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RIM‐binding proteins recruit BK‐channels to presynaptic release sites adjacent to voltage‐gated Ca(2+)‐channels
The active zone of presynaptic nerve terminals organizes the neurotransmitter release machinery, thereby enabling fast Ca(2+)‐triggered synaptic vesicle exocytosis. BK‐channels are Ca(2+)‐activated large‐conductance K(+)‐channels that require close proximity to Ca(2+)‐channels for activation and con...
Autores principales: | Sclip, Alessandra, Acuna, Claudio, Luo, Fujun, Südhof, Thomas C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092624/ https://www.ncbi.nlm.nih.gov/pubmed/29967030 http://dx.doi.org/10.15252/embj.201798637 |
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