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An Immune System-Modified Rat Model for Human Stem Cell Transplantation Research
Due to its lack of both innate and acquired immune responses to human cells, the NODSCIDIl2rγ(−/−) (NSG) mouse model has become an important tool for human stem cell research. When compared with the mouse, the rat is physiologically more similar to humans and offers advantages in preclinical efficac...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092637/ https://www.ncbi.nlm.nih.gov/pubmed/29983387 http://dx.doi.org/10.1016/j.stemcr.2018.06.004 |