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An Immune System-Modified Rat Model for Human Stem Cell Transplantation Research

Due to its lack of both innate and acquired immune responses to human cells, the NODSCIDIl2rγ(−/−) (NSG) mouse model has become an important tool for human stem cell research. When compared with the mouse, the rat is physiologically more similar to humans and offers advantages in preclinical efficac...

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Detalles Bibliográficos
Autores principales: Yang, Xinglong, Zhou, Jianlong, He, Jingjin, Liu, Jingfeng, Wang, Hui, Liu, Yachen, Jiang, Tao, Zhang, Qianbing, Fu, Xuemei, Xu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092637/
https://www.ncbi.nlm.nih.gov/pubmed/29983387
http://dx.doi.org/10.1016/j.stemcr.2018.06.004