COPS2 Antagonizes OCT4 to Accelerate the G2/M Transition of Mouse Embryonic Stem Cells

Proper regulation of the cell cycle is essential to safeguard the genomic integrity of embryonic stem cells (ESCs) while maintaining the fast proliferation rate. The pluripotency factor OCT4 has been shown to inhibit CDK1 activation, thus preventing mitotic entry and facilitating the maintenance of...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Peng, Ding, Nan, Zhang, Weiyu, Chen, Lingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092711/
https://www.ncbi.nlm.nih.gov/pubmed/30033083
http://dx.doi.org/10.1016/j.stemcr.2018.06.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092711/
https://www.ncbi.nlm.nih.gov/pubmed/30033083
http://dx.doi.org/10.1016/j.stemcr.2018.06.013

Ejemplares similares