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The discovery of pyridinium 1,2,4-triazines with enhanced performance in bioconjugation reactions

1,2,4-Triazines have recently been identified as versatile dienes participating in the inverse electron-demand Diels–Alder reaction with strained dienophiles. However, their widespread utility in bioconjugation reactions is still limited. Herein, we report a systematic study on the reactivity of var...

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Detalles Bibliográficos
Autores principales: Siegl, Sebastian J., Dzijak, Rastislav, Vázquez, Arcadio, Pohl, Radek, Vrabel, Milan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092722/
https://www.ncbi.nlm.nih.gov/pubmed/30155204
http://dx.doi.org/10.1039/c6sc05442k