Cargando…

Progressive Upregulation of Oxidative Metabolism Facilitates Plasmablast Differentiation to a T-Independent Antigen

Transitioning from a metabolically quiescent naive B cell to an antibody-secreting plasmablast requires division-dependent cellular differentiation. Though cell division demands significant ATP and metabolites, the metabolic processes used for ATP synthesis during plasmablast formation are not well...

Descripción completa

Detalles Bibliográficos
Autores principales: Price, Madeline J., Patterson, Dillon G., Scharer, Christopher D., Boss, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092755/
https://www.ncbi.nlm.nih.gov/pubmed/29898388
http://dx.doi.org/10.1016/j.celrep.2018.05.053