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Progressive Upregulation of Oxidative Metabolism Facilitates Plasmablast Differentiation to a T-Independent Antigen
Transitioning from a metabolically quiescent naive B cell to an antibody-secreting plasmablast requires division-dependent cellular differentiation. Though cell division demands significant ATP and metabolites, the metabolic processes used for ATP synthesis during plasmablast formation are not well...
Autores principales: | Price, Madeline J., Patterson, Dillon G., Scharer, Christopher D., Boss, Jeremy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092755/ https://www.ncbi.nlm.nih.gov/pubmed/29898388 http://dx.doi.org/10.1016/j.celrep.2018.05.053 |
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