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Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in intensive care unit patients with infection and sepsis patients: a patient-level meta-analysis of randomized trials

BACKGROUND: The clinical utility of serum procalcitonin levels in guiding antibiotic treatment decisions in patients with sepsis remains unclear. This patient-level meta-analysis based on 11 randomized trials investigates the impact of procalcitonin-guided antibiotic therapy on mortality in intensiv...

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Detalles Bibliográficos
Autores principales: Wirz, Yannick, Meier, Marc A., Bouadma, Lila, Luyt, Charles E., Wolff, Michel, Chastre, Jean, Tubach, Florence, Schroeder, Stefan, Nobre, Vandack, Annane, Djillali, Reinhart, Konrad, Damas, Pierre, Nijsten, Maarten, Shajiei, Arezoo, deLange, Dylan W., Deliberato, Rodrigo O., Oliveira, Carolina F., Shehabi, Yahya, van Oers, Jos A. H., Beishuizen, Albertus, Girbes, Armand R. J., de Jong, Evelien, Mueller, Beat, Schuetz, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092799/
https://www.ncbi.nlm.nih.gov/pubmed/30111341
http://dx.doi.org/10.1186/s13054-018-2125-7