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TAZ inhibition promotes IL-2-induced apoptosis of hepatocellular carcinoma cells by activating the JNK/F-actin/mitochondrial fission pathway

BACKGROUND: Cytokine-based cancer therapies have attracted a great deal of attention in recent years. Unfortunately, resistance to treatment limits the efficacy of these therapeutics. Therefore, the aim of our study was to explore the mechanism of IL-2-based therapy for hepatocellular carcinoma in a...

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Detalles Bibliográficos
Autores principales: Ji, Kaihua, Lin, Kaili, Wang, Yan, Du, Liqing, Xu, Chang, He, Ningning, Wang, Jinhan, Liu, Yang, Liu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092825/
https://www.ncbi.nlm.nih.gov/pubmed/30127666
http://dx.doi.org/10.1186/s12935-018-0615-y