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A carboxymethyl dextran-based polymeric conjugate as the antigen carrier for cancer immunotherapy

BACKGROUND: Antigen-specific cytotoxic T lymphocytes (CTLs), which eliminate target cells bearing antigenic peptides presented by surface major histocompatibility complex (MHC) class I molecules, play a key role in cancer immunotherapy. However, the majority of tumors are not immunologically rejecte...

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Detalles Bibliográficos
Autores principales: Shin, Jung Min, Song, Seok Ho, Vijayakameswara Rao, N., Lee, Eun Sook, Ko, Hyewon, Park, Jae Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092827/
https://www.ncbi.nlm.nih.gov/pubmed/30128166
http://dx.doi.org/10.1186/s40824-018-0131-0