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In-solution Y-chromosome capture-enrichment on ancient DNA libraries

BACKGROUND: As most ancient biological samples have low levels of endogenous DNA, it is advantageous to enrich for specific genomic regions prior to sequencing. One approach—in-solution capture-enrichment—retrieves sequences of interest and reduces the fraction of microbial DNA. In this work, we imp...

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Detalles Bibliográficos
Autores principales: Cruz-Dávalos, Diana I., Nieves-Colón, María A., Sockell, Alexandra, Poznik, G. David, Schroeder, Hannes, Stone, Anne C., Bustamante, Carlos D., Malaspinas, Anna-Sapfo, Ávila-Arcos, María C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092841/
https://www.ncbi.nlm.nih.gov/pubmed/30107783
http://dx.doi.org/10.1186/s12864-018-4945-x