Reversal of angiotensin ll-induced β-cell dedifferentiation via inhibition of NF-κb signaling

BACKGROUND: Type 2 diabetes mellitus (T2DM) is characterized by pancreatic β-cell failure, which arises from metabolic stress and results in β cell dedifferentiation, leading to β-cell death. Pathological activation of the renin–angiotensin system (RAS) contributes to increase cell stress, while RAS...

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Detalles Bibliográficos
Autores principales: Chen, Hong, Zhou, Wenjun, Ruan, Yuting, Yang, Lei, Xu, Ningning, Chen, Rongping, Yang, Rui, Sun, Jia, Zhang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092859/
https://www.ncbi.nlm.nih.gov/pubmed/30134927
http://dx.doi.org/10.1186/s10020-018-0044-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092859/
https://www.ncbi.nlm.nih.gov/pubmed/30134927
http://dx.doi.org/10.1186/s10020-018-0044-3

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