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Directed Evolution of Reprogramming Factors by Cell Selection and Sequencing

Directed biomolecular evolution is widely used to tailor and enhance enzymes, fluorescent proteins, and antibodies but has hitherto not been applied in the reprogramming of mammalian cells. Here, we describe a method termed directed evolution of reprogramming factors by cell selection and sequencing...

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Detalles Bibliográficos
Autores principales: Veerapandian, Veeramohan, Ackermann, Jan Ole, Srivastava, Yogesh, Malik, Vikas, Weng, Mingxi, Yang, Xiaoxiao, Jauch, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092915/
https://www.ncbi.nlm.nih.gov/pubmed/30078555
http://dx.doi.org/10.1016/j.stemcr.2018.07.002