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Directed Evolution of Reprogramming Factors by Cell Selection and Sequencing
Directed biomolecular evolution is widely used to tailor and enhance enzymes, fluorescent proteins, and antibodies but has hitherto not been applied in the reprogramming of mammalian cells. Here, we describe a method termed directed evolution of reprogramming factors by cell selection and sequencing...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092915/ https://www.ncbi.nlm.nih.gov/pubmed/30078555 http://dx.doi.org/10.1016/j.stemcr.2018.07.002 |