Secreted Frizzled-Related Protein-2 Inhibits Doxorubicin-Induced Apoptosis Mediated through the Akt-mTOR Pathway in Soleus Muscle

Doxorubicin (Dox) is a potent chemotherapeutic drug known for its dose-dependent and serious adverse effects, such as cardiotoxicity and myotoxicity. Dox-induced cardiotoxicity (DIC) and muscle toxicity (DIMT) have been studied; however, the mechanisms of Dox-induced apoptosis in soleus muscle are n...

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Detalles Bibliográficos
Autores principales: Merino, Hilda, Singla, Dinender K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093014/
https://www.ncbi.nlm.nih.gov/pubmed/30151071
http://dx.doi.org/10.1155/2018/6043064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093014/
https://www.ncbi.nlm.nih.gov/pubmed/30151071
http://dx.doi.org/10.1155/2018/6043064

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