2-Methoxyestradiol Attenuates Testosterone-Induced Benign Prostate Hyperplasia in Rats through Inhibition of HIF-1α/TGF-β/Smad2 Axis

Benign prostatic hyperplasia (BPH) is a common disorder in the male population. 2-Methoxyestradiol (2ME) is an end metabolite of estrogens with pleiotropic pharmacological properties. This study aimed to explore the potential ameliorative effects of 2ME against testosterone-induced BPH in rats. 2-Me...

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Detalles Bibliográficos
Autores principales: Abdel-Naim, Ashraf B., Neamatallah, Thikryat, Eid, Basma G., Esmat, Ahmed, Alamoudi, Abdulmohsin J., Abd El-Aziz, Gamal S., Ashour, Osama M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093036/
https://www.ncbi.nlm.nih.gov/pubmed/30154949
http://dx.doi.org/10.1155/2018/4389484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093036/
https://www.ncbi.nlm.nih.gov/pubmed/30154949
http://dx.doi.org/10.1155/2018/4389484

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