High-Resolution Single-Cell DNA Methylation Measurements Reveal Epigenetically Distinct Hematopoietic Stem Cell Subpopulations

Increasing evidence of functional and transcriptional heterogeneity in phenotypically similar cells examined individually has prompted interest in obtaining parallel methylome data. We describe the development and application of such a protocol to index-sorted murine and human hematopoietic cells th...

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Detalles Bibliográficos
Autores principales: Hui, Tony, Cao, Qi, Wegrzyn-Woltosz, Joanna, O'Neill, Kieran, Hammond, Colin A., Knapp, David J.H.F., Laks, Emma, Moksa, Michelle, Aparicio, Samuel, Eaves, Connie J., Karsan, Aly, Hirst, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093082/
https://www.ncbi.nlm.nih.gov/pubmed/30078558
http://dx.doi.org/10.1016/j.stemcr.2018.07.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093082/
https://www.ncbi.nlm.nih.gov/pubmed/30078558
http://dx.doi.org/10.1016/j.stemcr.2018.07.003

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