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Parallel factor ChIP provides essential internal control for quantitative differential ChIP-seq

A key challenge in quantitative ChIP combined with high-throughput sequencing (ChIP-seq) is the normalization of data in the presence of genome-wide changes in occupancy. Analysis-based normalization methods were developed for transcriptomic data and these are dependent on the underlying assumption...

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Detalles Bibliográficos
Autores principales: Guertin, Michael J, Cullen, Amy E, Markowetz, Florian, Holding, Andrew N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093181/
https://www.ncbi.nlm.nih.gov/pubmed/29672735
http://dx.doi.org/10.1093/nar/gky252