Activity of HSP90 Inhibiton in a Metastatic Lung Cancer Patient With a Germline BRCA1 Mutation

Heat shock proteins (HSPs) are molecular chaperones that maintain proteins in their correct conformation to ensure stability and protect carcinoma cells from apoptosis. HSP90 inhibitors (HSP90i) block multiple targets simultaneously, and despite responses in a selected population, no HSP90i have yet...

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Detalles Bibliográficos
Autores principales: Cedrés, Susana, Felip, Enriqueta, Cruz, Cristina, Martinez de Castro, Ana, Pardo, Nuria, Navarro, Alejandro, Martinez-Marti, Alex, Remon, Jordin, Zeron-Medina, Jorge, Balmaña, Judith, Llop-Guevara, Alba, Miquel, Josep M, Sansano, Irene, Nuciforo, Paolo, Mancuso, Francesco, Serra, Violeta, Vivancos, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093313/
https://www.ncbi.nlm.nih.gov/pubmed/29529211
http://dx.doi.org/10.1093/jnci/djy012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093313/
https://www.ncbi.nlm.nih.gov/pubmed/29529211
http://dx.doi.org/10.1093/jnci/djy012

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