Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma

Adrenocortical carcinoma (ACC) is an aggressive malignancy with poor response to chemotherapy. In this study, we evaluated a potential new treatment target for ACC, focusing on the mitochondrial reduced form of NAD phosphate (NADPH) generator nicotinamide nucleotide transhydrogenase (NNT). NNT has a...

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Detalles Bibliográficos
Autores principales: Chortis, Vasileios, Taylor, Angela E, Doig, Craig L, Walsh, Mark D, Meimaridou, Eirini, Jenkinson, Carl, Rodriguez-Blanco, Giovanny, Ronchi, Cristina L, Jafri, Alisha, Metherell, Louise A, Hebenstreit, Daniel, Dunn, Warwick B, Arlt, Wiebke, Foster, Paul A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093335/
https://www.ncbi.nlm.nih.gov/pubmed/29850793
http://dx.doi.org/10.1210/en.2018-00014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093335/
https://www.ncbi.nlm.nih.gov/pubmed/29850793
http://dx.doi.org/10.1210/en.2018-00014

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