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C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype

We previously investigated MET and its oncogenic mutants relevant to lung cancer in C. elegans. The inactive orthlogues of the receptor tyrosine kinase Eph and MET, namely vab-1 and RB2088 respectively, the temperature sensitive constitutively active form of KRAS, SD551 (let-60; GA89) and the inacti...

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Detalles Bibliográficos
Autores principales: Kanteti, Rajani, Dhanasingh, Immanuel, El-Hashani, Essam, Riehm, Jacob J., Stricker, Thomas, Nagy, Stanislav, Zaborin, Alexander, Zaborina, Olga, Biron, David, Alverdy, John C., Im, Hae Kyung, Siddiqui, Shahid, Padilla, Pamela A., Salgia, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093410/
https://www.ncbi.nlm.nih.gov/pubmed/26574927
http://dx.doi.org/10.1080/15384047.2015.1108495