Remodeling of the Acetylproteome by SIRT3 Manipulation Fails to Affect Insulin Secretion or β Cell Metabolism in the Absence of Overnutrition

SIRT3 is a nicotinamide adenine dinucleotide (NAD(+))- dependent mitochondrial protein deacetylase purported to influence metabolism through post-translational modification of metabolic enzymes. Fuel-stimulated insulin secretion, which involves mitochondrial metabolism, could be susceptible to SIRT3...

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Detalles Bibliográficos
Autores principales: Peterson, Brett S., Campbell, Jonathan E., Ilkayeva, Olga, Grimsrud, Paul A., Hirschey, Matthew D., Newgard, Christopher B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093627/
https://www.ncbi.nlm.nih.gov/pubmed/29972782
http://dx.doi.org/10.1016/j.celrep.2018.05.088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093627/
https://www.ncbi.nlm.nih.gov/pubmed/29972782
http://dx.doi.org/10.1016/j.celrep.2018.05.088

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