Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6

Calcium (Ca(2+)) plays a major role in numerous physiological processes. Ca(2+) homeostasis is tightly controlled by ion channels, the aberrant regulation of which results in various diseases including cancers. Calmodulin (CaM)–mediated Ca(2+)-induced inactivation is an ion channel regulatory mechan...

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Detalles Bibliográficos
Autores principales: Singh, Appu K., McGoldrick, Luke L., Twomey, Edward C., Sobolevsky, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093632/
https://www.ncbi.nlm.nih.gov/pubmed/30116787
http://dx.doi.org/10.1126/sciadv.aau6088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093632/
https://www.ncbi.nlm.nih.gov/pubmed/30116787
http://dx.doi.org/10.1126/sciadv.aau6088

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