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Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6
Calcium (Ca(2+)) plays a major role in numerous physiological processes. Ca(2+) homeostasis is tightly controlled by ion channels, the aberrant regulation of which results in various diseases including cancers. Calmodulin (CaM)–mediated Ca(2+)-induced inactivation is an ion channel regulatory mechan...
Autores principales: | Singh, Appu K., McGoldrick, Luke L., Twomey, Edward C., Sobolevsky, Alexander I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093632/ https://www.ncbi.nlm.nih.gov/pubmed/30116787 http://dx.doi.org/10.1126/sciadv.aau6088 |
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