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The binding of Chp2’s chromodomain to methylated H3K9 is essential for Chp2’s role in heterochromatin assembly in fission yeast

The binding of heterochromatin protein 1 (HP1) to lysine 9–methylated histone H3 (H3K9me) is an essential step in heterochromatin assembly. Chp2, an HP1-family protein in the fission yeast Schizosaccharomyces pombe, is required for heterochromatic silencing. Chp2 recruits SHREC, a multifunctional pr...

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Detalles Bibliográficos
Autores principales: Maksimov, Vladimir, Oya, Eriko, Tanaka, Mayo, Kawaguchi, Takayuki, Hachisuka, Aki, Ekwall, Karl, Bjerling, Pernilla, Nakayama, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093649/
https://www.ncbi.nlm.nih.gov/pubmed/30110338
http://dx.doi.org/10.1371/journal.pone.0201101