Cargando…
Antidepressive and anxiolytic effects of ostruthin, a TREK-1 channel activator
We screened a library of botanical compounds purified from plants of Vietnam for modulators of the activity of a two-pore domain K(+) channel, TREK-1, and we identified a hydroxycoumarin-related compound, ostruthin, as an activator of this channel. Ostruthin increased whole-cell TREK-1 channel curre...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093650/ https://www.ncbi.nlm.nih.gov/pubmed/30110354 http://dx.doi.org/10.1371/journal.pone.0201092 |