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Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs
Voltage-activated potassium (Kv) channels open to conduct K(+) ions in response to membrane depolarization, and subsequently enter non-conducting states through distinct mechanisms of inactivation. X-ray structures of detergent-solubilized Kv channels appear to have captured an open state even thoug...
Autores principales: | Matthies, Doreen, Bae, Chanhyung, Toombes, Gilman ES, Fox, Tara, Bartesaghi, Alberto, Subramaniam, Sriram, Swartz, Kenton Jon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093707/ https://www.ncbi.nlm.nih.gov/pubmed/30109985 http://dx.doi.org/10.7554/eLife.37558 |
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