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A novel partial volume correction method for accurate quantification of [(18)F] flortaucipir in the hippocampus

BACKGROUND: Off-target binding in the choroid plexus (CP) may cause spill-in of the tau PET tracer [(18)F] flortaucipir into the adjacent hippocampus region. The impact of this spill-in on hippocampal uptake was assessed using a novel partial volume correction method (PVC). METHODS: PVC was performe...

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Detalles Bibliográficos
Autores principales: Wolters, Emma E., Golla, Sandeep S. V., Timmers, Tessa, Ossenkoppele, Rik, van der Weijden, Chris W. J., Scheltens, Philip, Schwarte, Lothar, Schuit, Robert C., Windhorst, Albert D., Barkhof, Frederik, Yaqub, Maqsood, Lammertsma, Adriaan A., Boellaard, Ronald, van Berckel, Bart N. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093830/
https://www.ncbi.nlm.nih.gov/pubmed/30112620
http://dx.doi.org/10.1186/s13550-018-0432-2