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A novel partial volume correction method for accurate quantification of [(18)F] flortaucipir in the hippocampus
BACKGROUND: Off-target binding in the choroid plexus (CP) may cause spill-in of the tau PET tracer [(18)F] flortaucipir into the adjacent hippocampus region. The impact of this spill-in on hippocampal uptake was assessed using a novel partial volume correction method (PVC). METHODS: PVC was performe...
Autores principales: | Wolters, Emma E., Golla, Sandeep S. V., Timmers, Tessa, Ossenkoppele, Rik, van der Weijden, Chris W. J., Scheltens, Philip, Schwarte, Lothar, Schuit, Robert C., Windhorst, Albert D., Barkhof, Frederik, Yaqub, Maqsood, Lammertsma, Adriaan A., Boellaard, Ronald, van Berckel, Bart N. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093830/ https://www.ncbi.nlm.nih.gov/pubmed/30112620 http://dx.doi.org/10.1186/s13550-018-0432-2 |
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