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Peptide binding to cleaved CD31 dampens ischemia/reperfusion-induced intestinal injury

BACKGROUND: CD31 is a key transmembrane neutrophil immunoregulatory receptor. Mesenteric ischemia/reperfusion-induced neutrophil activation leads to a massive cleavage and shedding of the most extracellular domains of CD31 into plasma, enhancing the deleterious effect of neutrophil activation. We ha...

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Detalles Bibliográficos
Autores principales: Hoang, Quoc Thang, Nuzzo, Alexandre, Louedec, Liliane, Delbosc, Sandrine, Andreata, Francesco, Khallou-Laschet, Jamila, Assadi, Maksud, Montravers, Philippe, Longrois, Dan, Corcos, Olivier, Caligiuri, Giuseppina, Nicoletti, Antonino, Michel, Jean-Baptiste, Tran-Dinh, Alexy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093833/
https://www.ncbi.nlm.nih.gov/pubmed/30112663
http://dx.doi.org/10.1186/s40635-018-0192-3