Cholestasis induced liver pathology results in dysfunctional immune responses after arenavirus infection

Immune responses are critical for defense against pathogens. However, prolonged viral infection can result in defective T cell immunity, leading to chronic viral infection. We studied immune activation in response to arenavirus infection during cholestasis using bile duct ligation (BDL). We monitore...

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Detalles Bibliográficos
Autores principales: Lang, Elisabeth, Pozdeev, Vitaly I., Shinde, Prashant V., Xu, Haifeng C., Sundaram, Balamurugan, Zhuang, Yuan, Poschmann, Gereon, Huang, Jun, Stühler, Kai, Pandyra, Aleksandra A., Keitel, Verena, Häussinger, Dieter, Lang, Karl S., Lang, Philipp A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093869/
https://www.ncbi.nlm.nih.gov/pubmed/30111770
http://dx.doi.org/10.1038/s41598-018-30627-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093869/
https://www.ncbi.nlm.nih.gov/pubmed/30111770
http://dx.doi.org/10.1038/s41598-018-30627-y

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