COPD is accompanied by co-ordinated transcriptional perturbation in the quadriceps affecting the mitochondria and extracellular matrix

Skeletal muscle dysfunction is a frequent extra-pulmonary manifestation of Chronic Obstructive Pulmonary Disease (COPD) with implications for both quality of life and survival. The underlying biology nevertheless remains poorly understood. We measured global gene transcription in the quadriceps usin...

Descripción completa

Detalles Bibliográficos
Autores principales: Willis-Owen, Saffron A. G., Thompson, Anna, Kemp, Paul R., Polkey, Michael I., Cookson, William O. C. M., Moffatt, Miriam F., Natanek, Samantha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093887/
https://www.ncbi.nlm.nih.gov/pubmed/30111857
http://dx.doi.org/10.1038/s41598-018-29789-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093887/
https://www.ncbi.nlm.nih.gov/pubmed/30111857
http://dx.doi.org/10.1038/s41598-018-29789-6

Ejemplares similares