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Wnt pathway is involved in 5-FU drug resistance of colorectal cancer cells

Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide. 5-Fluorouracil (5-FU) is widely used in the treatment of cancers, but its antineoplastic activity is limited in drug-resistant cancer cells. To investigate the detailed mechanism of 5-FU resistance, we developed...

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Detalles Bibliográficos
Autores principales: He, Lingfeng, Zhu, Hong, Zhou, Shiying, Wu, Ting, Wu, Huan, Yang, Huan, Mao, Huiwen, SekharKathera, Chandra, Janardhan, Avilala, Edick, Ashlin M., Zhang, Anna, Hu, Zhigang, Pan, Feiyan, Guo, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093888/
https://www.ncbi.nlm.nih.gov/pubmed/30111797
http://dx.doi.org/10.1038/s12276-018-0128-8