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Chemical genetic-based phenotypic screen reveals novel regulators of gluconeogenesis in human primary hepatocytes

Insulin resistance is a pathophysiological hallmark of type 2 diabetes and nonalcoholic fatty liver disease. Under the condition of fat accumulation in the liver, suppression of hepatic glucose production by insulin is diminished. In order to gain deeper understanding of dysregulation of glucose pro...

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Detalles Bibliográficos
Autores principales: Zou, Haixia, Liu, Qian, Meng, Li, Zhou, Jingye, Da, Chenxiao, Wu, Xikun, Jiang, Lichun, Shou, Jianyong, Hua, Haiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093908/
https://www.ncbi.nlm.nih.gov/pubmed/30131871
http://dx.doi.org/10.1038/s41525-018-0062-7