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Chemical genetic-based phenotypic screen reveals novel regulators of gluconeogenesis in human primary hepatocytes
Insulin resistance is a pathophysiological hallmark of type 2 diabetes and nonalcoholic fatty liver disease. Under the condition of fat accumulation in the liver, suppression of hepatic glucose production by insulin is diminished. In order to gain deeper understanding of dysregulation of glucose pro...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093908/ https://www.ncbi.nlm.nih.gov/pubmed/30131871 http://dx.doi.org/10.1038/s41525-018-0062-7 |