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Human tissue-engineered skeletal muscle: a novel 3D in vitro model for drug disposition and toxicity after intramuscular injection

The development of laboratory-grown tissues, referred to as organoids, bio-artificial tissue or tissue-engineered constructs, is clearly expanding. We describe for the first time how engineered human muscles can be applied as a pre- or non-clinical model for intramuscular drug injection to further d...

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Detalles Bibliográficos
Autores principales: Gholobova, D., Gerard, M., Decroix, L., Desender, L., Callewaert, N., Annaert, P., Thorrez, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093918/
https://www.ncbi.nlm.nih.gov/pubmed/30111779
http://dx.doi.org/10.1038/s41598-018-30123-3