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Human tissue-engineered skeletal muscle: a novel 3D in vitro model for drug disposition and toxicity after intramuscular injection
The development of laboratory-grown tissues, referred to as organoids, bio-artificial tissue or tissue-engineered constructs, is clearly expanding. We describe for the first time how engineered human muscles can be applied as a pre- or non-clinical model for intramuscular drug injection to further d...
Autores principales: | Gholobova, D., Gerard, M., Decroix, L., Desender, L., Callewaert, N., Annaert, P., Thorrez, L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093918/ https://www.ncbi.nlm.nih.gov/pubmed/30111779 http://dx.doi.org/10.1038/s41598-018-30123-3 |
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