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Flt3 ligand treatment reduces enterovirus A71 lethality in mice with enhanced B cell responses

Enterovirus A71 (EV-A71) infection can induce encephalitis, which causes death or long-term neurological sequelae, especially in young children. Using a murine infection model, we searched for anti-EV-A71 agents, because effective therapies are not available to control fatal infection. In EV-A71-inf...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Wen, Wang, Li-Chiu, Lee, Chien-Kuo, Chen, Shun-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093920/
https://www.ncbi.nlm.nih.gov/pubmed/30111869
http://dx.doi.org/10.1038/s41598-018-30631-2