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The impact of SPARC on age-related cardiac dysfunction and fibrosis in Drosophila
Tissue fibrosis, an accumulation of extracellular matrix proteins such as collagen, accompanies cardiac ageing in humans and this is linked to an increased risk of cardiac failure. The mechanisms driving age-related tissue fibrosis and cardiac dysfunction are unclear, yet clinically important. Droso...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094046/ https://www.ncbi.nlm.nih.gov/pubmed/29032244 http://dx.doi.org/10.1016/j.exger.2017.10.011 |