Zinc depletion induces ribosome hibernation in mycobacteria

Bacteria respond to zinc starvation by replacing ribosomal proteins that have the zinc-binding CXXC motif (C+) with their zinc-free (C−) paralogues. Consequences of this process beyond zinc homeostasis are unknown. Here, we show that the C− ribosome in Mycobacterium smegmatis is the exclusive target...

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Detalles Bibliográficos
Autores principales: Li, Yunlong, Sharma, Manjuli R., Koripella, Ravi K., Yang, Yong, Kaushal, Prem S., Lin, Qishan, Wade, Joseph T., Gray, Todd A., Derbyshire, Keith M., Agrawal, Rajendra K., Ojha, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094098/
https://www.ncbi.nlm.nih.gov/pubmed/30038002
http://dx.doi.org/10.1073/pnas.1804555115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094098/
https://www.ncbi.nlm.nih.gov/pubmed/30038002
http://dx.doi.org/10.1073/pnas.1804555115

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