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Zinc depletion induces ribosome hibernation in mycobacteria
Bacteria respond to zinc starvation by replacing ribosomal proteins that have the zinc-binding CXXC motif (C+) with their zinc-free (C−) paralogues. Consequences of this process beyond zinc homeostasis are unknown. Here, we show that the C− ribosome in Mycobacterium smegmatis is the exclusive target...
Autores principales: | Li, Yunlong, Sharma, Manjuli R., Koripella, Ravi K., Yang, Yong, Kaushal, Prem S., Lin, Qishan, Wade, Joseph T., Gray, Todd A., Derbyshire, Keith M., Agrawal, Rajendra K., Ojha, Anil K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094098/ https://www.ncbi.nlm.nih.gov/pubmed/30038002 http://dx.doi.org/10.1073/pnas.1804555115 |
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