Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation

Ectodysplasin A (Eda) signaling activates NF-κB during skin appendage formation, but how Eda controls specific gene transcription remains unclear. Here, we find that Eda triggers the formation of an NF-κB–associated SWI/SNF (BAF) complex in which p50/RelB recruits a linker protein, Tfg, that interac...

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Detalles Bibliográficos
Autores principales: Sima, Jian, Yan, Zhijiang, Chen, Yaohui, Lehrmann, Elin, Zhang, Yongqing, Nagaraja, Ramaiah, Wang, Weidong, Wang, Zhong, Schlessinger, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094125/
https://www.ncbi.nlm.nih.gov/pubmed/30037996
http://dx.doi.org/10.1073/pnas.1800930115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094125/
https://www.ncbi.nlm.nih.gov/pubmed/30037996
http://dx.doi.org/10.1073/pnas.1800930115

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